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Improvement of Signs and Symptoms of Chronic Venous Insufficiency and Microangiopathy with Pycnogenol[R]: A Prospective, Controlled Study (Report)

eBook details

Title: Improvement of Signs and Symptoms of Chronic Venous Insufficiency and Microangiopathy with Pycnogenol[R]: A Prospective, Controlled Study (Report)
Author : Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
Release Date : January 01, 2010
Genre: Life Sciences,Books,Science & Nature,
Pages : * pages
Size : 231 KB

Description

ABSTRACT The aim of this study was to evaluate the clinical efficacy of standardized French maritime pine bark extract Pycnogenol[R] in patients with severe chronic venous insufficiency (CVI). 98 subjects with symptomatic CVI and edema were randomly assigned to one group treated with 150 mg Pycnogenol a day only, another group with stockings only and a third group with both Pycnogenol and elastic stockings. The average ambulatory venous pressure (AVP) at inclusion was 58 [+ or -] 7 mm Hg (range 48-60 mm Hg) with a refilling time (RT) 12s (average 7 [+ or -] 2 s). The duration of the disease was on average 6.0 [+ or -] 3.1 years. There were no differences in AVP or RT among the 3 groups at inclusion and microcirculatory and clinical evaluations were comparable.